MedlinePlus
MedlinePlus consumer health — clinical code lookup across seven vocabularies, health-topic search in English and Spanish, and genetics condition and gene summaries.
Genetics Condition
MedlinePlus Genetics — one condition summary from the download bundle, rung 1 (direct). There is no directory index for these files (condition/, gene/ and /xml/ all 404), so the
/v1/health:medlineplus/genetics-conditionParameters
| Name | Type | In | Description |
|---|---|---|---|
| slug | string | query | Condition slug as it appears in the MedlinePlus Genetics URL. Required. |
Example response
{"project":"health:medlineplus", "data": {"url":"https://medlineplus.gov/genetics/condition/alzheimer-disease","name":"Alzheimer disease","slug":"alzheimer-disease","provider":"medlineplus","reviewed":"2019-05", "sections": [ {"html":"<p>Alzheimer disease is a degenerative disease of the brain that causes dementia, which is a gradual loss of memory, judgment, and ability to function. This disorder usually appears in people older than age 65, but less common forms of the disease appear earlier in adulthood.</p><p>Memory loss is the most common sign of Alzheimer disease. Forgetfulness may be subtle at first, but the loss of memory worsens over time until it interferes with most aspects of daily living. Even in familiar settings, a person with Alzheimer disease may get lost or become confused. Routine tasks such as preparing meals, doing laundry, and performing other household chores can be challenging. Additionally, it may become difficult to recognize people and name objects. Affected people increasingly require help with dressing, eating, and personal care.</p><p>As the disorder progresses, some people with Alzheimer disease experience personality and behavioral changes and have trouble interacting in a socially appropriate manner. Other common symptoms include agitation, restlessness, withdrawal, and loss of language skills. People with this disease usually require total care during the advanced stages of the disease.</p><p>Affected individuals usually survive 8 to 10 years after the appearance of symptoms, but the course of the disease can range from 1 to 25 years. Survival is usually shorter in individuals diagnosed after age 80 than in those diagnosed at a younger age. Death usually results from pneumonia, malnutrition, or general body wasting (inanition).</p><p>Alzheimer disease can be classified as early-onset or late-onset. The signs and symptoms of the early-onset form appear between a person's thirties and mid-sixties, while the late-onset form appears during or after a person's mid-sixties. The early-onset form is much less common than the late-onset form, accounting for less than 10 percent of all cases of Alzheimer disease.</p>","role":"description" } ], "synonyms": [ "AD", "Alzheimer dementia (AD)", "Alzheimer sclerosis", "Alzheimer syndrome", "Alzheimer's disease", "Alzheimer-type dementia (ATD)", "DAT", "Familial Alzheimer disease (FAD)" ],"published":"2023-03-23", "relatedGenes": [ {"url":"https://medlineplus.gov/genetics/gene/app","symbol":"APP" }, {"url":"https://medlineplus.gov/genetics/gene/apoe","symbol":"APOE" }, {"url":"https://medlineplus.gov/genetics/gene/psen1","symbol":"PSEN1" }, {"url":"https://medlineplus.gov/genetics/gene/psen2","symbol":"PSEN2" } ], "crossReferences": [ {"db":"GTR","key":"C0002395" }, {"db":"GTR","key":"C1843013" }, {"db":"GTR","key":"C1847200" }, {"db":"GTR","key":"C1863051" }, {"db":"ICD-10-CM","key":"G30" }, {"db":"ICD-10-CM","key":"G30.0" }, {"db":"ICD-10-CM","key":"G30.1" }, {"db":"ICD-10-CM","key":"G30.8" } ], "inheritancePatterns": [ {"code":"u","description":"Pattern unknown" }, {"code":"ad","description":"Autosomal dominant" } ] },"timestamp":"2026-08-30T00:49:29Z"}
Errors
- 401Missing or invalid x-api-key
- 404Not found or private
- 429Rate limit or monthly quota reached
Genetics Gene
MedlinePlus Genetics — one gene summary from the download bundle, rung 1 (direct). The .json extension and the application/json content-type both lie here: the body is an XML
/v1/health:medlineplus/genetics-geneParameters
| Name | Type | In | Description |
|---|---|---|---|
| symbol | string | query | Official gene symbol as used by MedlinePlus Genetics. Required. |
Example response
{"project":"health:medlineplus", "data": {"url":"https://medlineplus.gov/genetics/gene/brca1","name":"BRCA1 DNA repair associated","geneId":"21728","symbol":"BRCA1","provider":"medlineplus","reviewed":"2015-09", "sections": [ {"html":"<p>The <i>BRCA1</i> gene provides instructions for making a protein that acts as a tumor suppressor. Tumor suppressor proteins help prevent cells from growing and dividing too rapidly or in an uncontrolled way.</p><p>The BRCA1 protein is involved in repairing damaged DNA. In the nucleus of many types of normal cells, the BRCA1 protein interacts with several other proteins to mend breaks in DNA. These breaks can be caused by natural and medical radiation or other environmental exposures, and they also occur when chromosomes exchange genetic material in preparation for cell division. By helping to repair DNA, the BRCA1 protein plays a critical role in maintaining the stability of a cell's genetic information.</p><p>Research suggests that the BRCA1 protein also regulates the activity of other genes and plays an essential role in embryonic development. To carry out these functions, the BRCA1 protein interacts with many other proteins, including other tumor suppressors and proteins that regulate cell division.</p>","role":"function" } ], "synonyms": [ "BRCA1 gene", "BRCA1_HUMAN", "BRCC1", "breast cancer 1", "breast cancer 1 gene", "breast cancer 1, early onset", "breast cancer 1, early onset gene", "breast cancer type 1 susceptibility gene" ],"published":"2025-04-03", "crossReferences": [ {"db":"NCBI Gene","key":"672" }, {"db":"OMIM","key":"113705" } ], "relatedConditions": [ {"url":"https://medlineplus.gov/genetics/condition/breast-cancer","name":"Breast cancer" }, {"url":"https://medlineplus.gov/genetics/condition/fanconi-anemia","name":"Fanconi anemia" }, {"url":"https://medlineplus.gov/genetics/condition/prostate-cancer","name":"Prostate cancer" }, {"url":"https://medlineplus.gov/genetics/condition/ovarian-cancer","name":"Ovarian cancer" }, {"url":"https://medlineplus.gov/genetics/condition/cholangiocarcinoma","name":"Cholangiocarcinoma" } ] },"timestamp":"2026-08-30T00:49:29Z"}
Errors
- 401Missing or invalid x-api-key
- 404Not found or private
- 429Rate limit or monthly quota reached
Lookup
MedlinePlus Connect — consumer health pages for a clinical code, rung 1 (direct). Atom feed rendered as JSON: every scalar arrives wrapped in `._value`, and omitting
/v1/health:medlineplus/lookupParameters
| Name | Type | In | Description |
|---|---|---|---|
| codeSystem | enum | query | Clinical vocabulary the code belongs to. One of icd10cm, icd9cm, snomed, rxcui, ndc, loinc, cpt. Required. |
| code | string | query | Code to look up inside the chosen vocabulary. Required. |
| language | enum | query | Language of the returned pages. Default en. One of en, es. |
Example response
{"project":"health:medlineplus", "data": {"code":"E11.9","count":3, "items": [ {"id":"tag: medlineplus.gov, 2026-30-08:/diabetestype2.html?utm_source=mplusconnect&utm_medium=application","url":"https://medlineplus.gov/diabetestype2.html?utm_source=mplusconnect&utm_medium=service", "links": [ {"rel":"alternate","url":"https://medlineplus.gov/diabetestype2.html?utm_source=mplusconnect&utm_medium=service" } ],"title":"Diabetes Type 2","summary":"<h3>What is type 2 diabetes?</h3> \n<p>Type 2 <a href=\"https://medlineplus.gov/diabetes.html?utm_source=mplusconnect\">diabetes</a> is a disease in which your blood glucose, or <a hr…","updatedAt":"2026-08-30T00:46:12Z","summaryType":"html" }, {"id":"tag: medlineplus.gov, 2026-30-08:/genetics/condition/type-2-diabetes?utm_source=mplusconnect&utm_medium=application","url":"https://medlineplus.gov/genetics/condition/type-2-diabetes?utm_source=mplusconnect&utm_medium=service", "links": [ {"rel":"alternate","url":"https://medlineplus.gov/genetics/condition/type-2-diabetes?utm_source=mplusconnect&utm_medium=service" } ],"title":"Type 2 diabetes","summary":"<p>Type 2 diabetes is a disorder characterized by abnormally high levels of blood glucose, also called blood sugar. In this form of diabetes, the body stops using and making insuli…","updatedAt":"2026-08-30T00:46:12Z","summaryType":"html" }, {"id":"tag: www.niddk.nih.gov, 2026-30-08:/health-information/diabetes/overview/what-is-diabetes/type-2-diabetes?utm_medium=ehr+service&utm_source=medlineplus+connect","url":"https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/type-2-diabetes?utm_medium=ehr+service&utm_source=medlineplus+connect", "links": [ {"rel":"alternate","url":"https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/type-2-diabetes?utm_medium=ehr+service&utm_source=medlineplus+connect" } ],"title":"Type 2 Diabetes","summary":"Learn about the symptoms of type 2 diabetes, what causes the disease, how it’s diagnosed, and steps you can take to help prevent or delay type 2 diabetes.","updatedAt":"2026-08-30T00:46:12Z","summaryType":"html" } ],"title":"MedlinePlus Connect", "author": {"url":"https://www.nlm.nih.gov","name":"U.S. National Library of Medicine" }, "matched": {"code":"E11.9","system":"ICD10CM" },"language":"en","provider":"medlineplus","subtitle":"MedlinePlus Connect results for ICD-10-CM E11.9","updatedAt":"2026-08-30T00:46:12Z","codeSystem":"icd10cm" },"timestamp":"2026-08-30T00:49:29Z"}
Errors
- 401Missing or invalid x-api-key
- 404Not found or private
- 429Rate limit or monthly quota reached
Search Topics
MedlinePlus health-topic search (NLM wsearch) — rung 1 (direct). The response is XML whose content is HTML-entity-escaped, and what decodes out of it still carries <span class="qt0"> highlight wrappers; an unknown db answers 200 with an
/v1/health:medlineplus/search-topicsParameters
| Name | Type | In | Description |
|---|---|---|---|
| term | string | query | Search terms matched against MedlinePlus health topics. Required. |
| language | enum | query | Topic collection to search. Default en. One of en, es. |
| page | number | query | Page number. Default 1. |
| limit | number | query | Items per page. Default 10, max 100. |
| detail | enum | query | Amount of content per topic. Default brief. One of brief, topic, all. |
Example response
{"project":"health:medlineplus", "data": {"page":1,"term":"asthma","count":3, "items": [ {"url":"https://medlineplus.gov/asthma.html","rank":1,"title":"Asthma", "groups": [ "Lungs and Breathing", "Immune System" ],"snippet":"What is asthma? Asthma is a chronic (long-term) lung disease. It affects your airways, the tubes that carry air in and out of your lungs. When you have ...","summary":"What is asthma? Asthma is a chronic (long-term) lung disease. It affects your airways, the tubes that carry air in and out of your lungs. When you have asthma, your airways can bec…", "altTitles": [ "Bronchial Asthma" ], "meshTerms": [ "Asthma" ],"organizationName":"National Library of Medicine" }, {"url":"https://medlineplus.gov/asthmainchildren.html","rank":0,"title":"Asthma in Children", "groups": [ "Children and Teenagers", "Lungs and Breathing", "Immune System" ],"snippet":"What is asthma? Asthma is a chronic (long-term) lung disease. It affects your airways, the tubes that carry air in and out of your lungs. When you have ...","summary":"What is asthma? Asthma is a chronic (long-term) lung disease. It affects your airways, the tubes that carry air in and out of your lungs. When you have asthma, your airways can bec…", "altTitles": [ "Childhood Asthma", "Pediatric asthma" ], "meshTerms": [ "Asthma" ],"organizationName":"National Library of Medicine" }, {"url":"https://medlineplus.gov/allergy.html","rank":2,"title":"Allergy", "groups": [ "Ear, Nose and Throat", "Immune System" ],"snippet":"An allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies often are sensitive to more ...","summary":"An allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies often are sensitive to more than one thing. Substances…", "altTitles": [ "Allergic Rhinitis", "Hypersensitivity" ], "meshTerms": [ "Hypersensitivity" ],"organizationName":"National Library of Medicine" } ],"limit":3,"total":55,"hasMore":true,"language":"en","nextPage":2,"provider":"medlineplus" },"timestamp":"2026-08-30T00:49:29Z"}
Errors
- 401Missing or invalid x-api-key
- 404Not found or private
- 429Rate limit or monthly quota reached
Try it
Live request with your key
const data = await client.run( "health:medlineplus", "genetics-condition", { slug: "alzheimer-disease" });
MedlinePlus
MedlinePlus consumer health — clinical code lookup across seven vocabularies, health-topic search in English and Spanish, and genetics condition and gene summaries.
MedlinePlus Genetics — one condition summary from the download bundle, rung 1 (direct). There is no directory index for these files (condition/, gene/ and /xml/ all 404), so the
/v1/…medlineplus/genetics-conditionTry it
Parameters
slug
string · query · required
Condition slug as it appears in the MedlinePlus Genetics URL.
Example response
{"project":"health:medlineplus", "data": {"url":"https://medlineplus.gov/genetics/condition/alzheimer-disease","name":"Alzheimer disease","slug":"alzheimer-disease","provider":"medlineplus","reviewed":"2019-05", "sections": [ {"html":"<p>Alzheimer disease is a degenerative disease of the brain that causes dementia, which is a gradual loss of memory, judgment, and ability to function. This disorder usually appears in people older than age 65, but less common forms of the disease appear earlier in adulthood.</p><p>Memory loss is the most common sign of Alzheimer disease. Forgetfulness may be subtle at first, but the loss of memory worsens over time until it interferes with most aspects of daily living. Even in familiar settings, a person with Alzheimer disease may get lost or become confused. Routine tasks such as preparing meals, doing laundry, and performing other household chores can be challenging. Additionally, it may become difficult to recognize people and name objects. Affected people increasingly require help with dressing, eating, and personal care.</p><p>As the disorder progresses, some people with Alzheimer disease experience personality and behavioral changes and have trouble interacting in a socially appropriate manner. Other common symptoms include agitation, restlessness, withdrawal, and loss of language skills. People with this disease usually require total care during the advanced stages of the disease.</p><p>Affected individuals usually survive 8 to 10 years after the appearance of symptoms, but the course of the disease can range from 1 to 25 years. Survival is usually shorter in individuals diagnosed after age 80 than in those diagnosed at a younger age. Death usually results from pneumonia, malnutrition, or general body wasting (inanition).</p><p>Alzheimer disease can be classified as early-onset or late-onset. The signs and symptoms of the early-onset form appear between a person's thirties and mid-sixties, while the late-onset form appears during or after a person's mid-sixties. The early-onset form is much less common than the late-onset form, accounting for less than 10 percent of all cases of Alzheimer disease.</p>","role":"description" } ], "synonyms": [ "AD", "Alzheimer dementia (AD)", "Alzheimer sclerosis", "Alzheimer syndrome", "Alzheimer's disease", "Alzheimer-type dementia (ATD)", "DAT", "Familial Alzheimer disease (FAD)" ],"published":"2023-03-23", "relatedGenes": [ {"url":"https://medlineplus.gov/genetics/gene/app","symbol":"APP" }, {"url":"https://medlineplus.gov/genetics/gene/apoe","symbol":"APOE" }, {"url":"https://medlineplus.gov/genetics/gene/psen1","symbol":"PSEN1" }, {"url":"https://medlineplus.gov/genetics/gene/psen2","symbol":"PSEN2" } ], "crossReferences": [ {"db":"GTR","key":"C0002395" }, {"db":"GTR","key":"C1843013" }, {"db":"GTR","key":"C1847200" }, {"db":"GTR","key":"C1863051" }, {"db":"ICD-10-CM","key":"G30" }, {"db":"ICD-10-CM","key":"G30.0" }, {"db":"ICD-10-CM","key":"G30.1" }, {"db":"ICD-10-CM","key":"G30.8" } ], "inheritancePatterns": [ {"code":"u","description":"Pattern unknown" }, {"code":"ad","description":"Autosomal dominant" } ] },"timestamp":"2026-08-30T00:49:29Z"}
Errors
- 401Missing or invalid x-api-key
- 404Not found or private
- 429Rate limit or monthly quota reached
Code
const data = await client.run( "health:medlineplus", "genetics-condition", { slug: "alzheimer-disease" });